This week’s CotW includes the landscape of biomarkers and clinical trials for Alzheimer’s disease. There is significant clustering around two biomarkers, but many interesting emerging biomarkers in clinical trials. Gray: Disease Blue: Biomarkers...
As previously reported, psychiatric drugs are among the most likely to be involved genetically-mediated drug toxicity, due to mutations in various metabolizing cytochrome p450 genes. We conducted an informal survey on a LinkedIn group for psychiatrists, asking them...
Here are the basic facts that rescue the dramatic headline from being mere hyperbole: 1. Some of the drugs used to treat schizophrenia are associated with increased rates of sudden cardiac death [1]; 2. The 2 schizophrenia drugs associated with the highest rates of...
We have just conducted a review of the biomarkers in drug labels to complete the population of the theranostic clinical biomarkers in BiomarkerBase™, and it was not surprising to note how well-represented the cytochrome p450’s are in the labels of approved...
