New Approaches To Identifying Targeted Therapeutics

Making the maximum use of discoveries that have already been made is a central interest of mine, and a couple of recent articles have described novel ways that targeted therapies might be “discovered” for individual patients. A group at MIT has developed a...

Regulatory Delays Are Keeping the Diagnostics Industry in Limbo

An FDA official recently stated that the final version of the draft guidance regarding regulation of laboratory-developed tests (LDTs) is not likely to be released before the end of this year. Elizabeth Mansfield, director of personalized medicine at the FDA’s...

Watson Tackles the Genomic Interpretation Gap

A fascinating article was just published by Ariana Cha in the Washington Post describing how IBM’s Watson is being used at 14 major cancer centers to help interpret genomic data. The program is still in the early stages, which means that Watson is still...

The Two Biggest Ideas for Personalized Medicine

Nature recently published two articles, within a day of each other as it would happen, that describe challenges confronting the two biggest ideas for advancing personalized medicine. One-Person Trials The first idea, described in an article by Nicholas J. Schork,...