June 2014 - Amplion

10 Biomarkers to Watch in Oncology

Jun 26, 2014 | News

We decided to mine the biomarkers being used in clinical trials for interesting test development opportunities, and we began with Oncology as the first therapeutic area to explore. Our basic methodology was to identify biomarkers that are in regular (and hopefully...

Biomarkers In Clinical Trials: 80% Are Used In Two Or More Therapeutic Areas

Jun 18, 2014 | News

We have been mining BiomarkerBase a bit more deeply to understand biomarker use across different therapeutic areas, and are frankly a bit surprised by how many biomarkers cross multiple TAs. Of the 700 biomarker targets that we have been able to extract so far from...

Clinical Trials Are Increasingly Using Multi-Biomarker Approaches

Jun 17, 2014 | News

While multi-biomarker approaches are certainly going to become more common (key quote: “We really are moving away from this one drug, one biomarker, one companion diagnostic,” Dr Richard Pazdur, FDA’s oncology chief), this article identifies one key...

Industry Report: Using Biomarkers To Accelerate Clinical Development

Jun 13, 2014 | Biomarkers, News

PPD has published a very nice white paper that provides an overview of the ways in which biomarkers are used in the clinical stages of drug development. Among the more interesting data and case studies in the report (and there is plenty of both), is a figure that...

Genetic Testing Is Becoming More Routine At Cancer Hospitals

Jun 11, 2014 | News

This article provides a nice summary of progress in using biomarkers to help treat cancer. One of the key takeaways is how much potential there is to understand the precise differences in tumors, and how different drugs will affect each of them. The article references...

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