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Precision Medicine Innovation Not Just a Numbers Game

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We published a revision to our Precision Medicine Scorecard: Drug Company Edition last month. As John Audette rightfully notes, there are multiple factors in a pharmaceutical company’s contribution to precision medicines:

  • How many precision medicines a company currently markets;
  • The percentages of the company’s recent clinical trials that involve biomarkers;
  • The number of novel oncology drugs the company has in its pipeline;
  • The number of “proprietary” biomarkers the company is using in its clinical trials.

While we continue to highlight why biomarkers are critical to precision medicine we wanted to test the raw usage of biomarkers by the top 10 pharma against each other to further support John’s conclusions in the Scorecard.

We decided to leverage our new Workspace feature in BiomarkerBase to compare our ranking to general use of biomarkers by each of the top 10 pharma companies as compared against each other.  Our process was to simply compare each of the top 10 pharma against each other in biomarker usage in oncology.  We chose oncology because each top pharma company is well represented.

OncologyBiomarkersUsedInOncologyTop10.png

 

The top 5 pharmaceutical companies, by our Precision Medicine Scorecard, are using more biomarkers than anyone else.  However, second place Roche is more closely associated with seventh place Merck.  Third place AstraZeneca is below seventh place Merck.

More research is need to determine what practices are contributing to pharmaceutical company’s commercial success in precision medicine.  What do the biomarker practices look like at, for instance, Novartis?

 

NovartisRocheAstraZenecaPfizerGSKBoehringer IngelheimMerckCelgeneEisaiJ&J
Novartis100591181424894491719
Roche1637915016871116461724
AstraZeneca17513217719669125712127
Pfizer12493671555196541915
GSK11073481175182451210
Boehringer Ingelheim199159104196234152742736
Merck1581177315417865562321
Celgene2301641362292581041733145
Eisai2642011522562911232069747
J&J2501921422442731161889531
 Totals16731231860164118956981232587194248